Andy,
grind a slot into the back of the slab with a rodding blade:
http://www.defusco.com/specialty-fabricating-tools-granite-rodding-blade-c-25_35_710.htmlThen insert a piece of steel (electricians fish tape or 1/8" x 1/4" steel rod) into the slot and glue in place with epoxy. This will act like a backbone and strengthen the countertop while you are transporting it.
Make sure you have adequate support from beneath when you do your install. 5/8" plywood as a subdeck works very well. Install with silicone.
It is perfectly acceptable to drill the spigot holes after countertop installation, in fact it is standard operating procedure. This bit is a dry bit that is fast and aggressive so you won't be putting any pressure onto your slab:
http://www.defusco.com/38%E2%80%9D-58%E2%80%9D11-seg-dry-stone-core-bit-vbb-p-2377.htmlGlad to be of service,
Mark